Werner Kloas

Prof. Dr. Werner Kloas

IGB-Abteilung: (A5) Ökophysiologie und Aquakultur
Funktion: Abteilungsleiter/in
E-Mail-Adresse:
Telefonnummer: +49 (0)30 64181 630
Faxnummer: +49 (0)30 64181 663
Standort: Müggelseedamm 310, 12587 Berlin
Raum: 414
  • Lebenslauf
  • Forschung
  • Publikationen
  • Lehre
  • Sonstiges

Lebenslauf

1966-1978 Abschluß mit Abitur am Bismarckgymnasium Karlsruhe
1979-1986 Studium der Biologie und Sport für das höhere Lehramt an Gymnasien, Staatsexamina an der Universität Karlsruhe Thema der Zulassungsarbeit: "Untersuchungen zur Regulation der Nebennierensekretion von Amphibien (Xenopus laevis) durch humorale Faktoren und Metopiron in vitro"
1984-1986 Wissenschaftliche Hilfskraft am Zoologischen Institut II der Universität Karlsruhe
1986-1991 Wissenschaftlicher Mitarbeiter am Zoologischen Institut II der Universität Karlsruhe (ab 08/1988 gefördert durch DFG Ha78/36)
1986-1990 Promotion an der Fakultät für Bio- und Geowissenschaften der Universität Karlsruhe; Durchführung der Arbeiten zu ungefähr gleichen Teilen am Zoologischen Institut II der Universität Karlsruhe und der Abtlg. Reproduktionsbiologie des Deutschen Primaten Zentrums Göttingen
1991-1992 Postdoctoral fellow, European Institute for Peptide Research, CNRS, INSERM,University of Rouen, Mont-Saint-Aignan, France; Stipendiat der DFG (Kl 745/1-1) 1992-1993 Wissenschaftlicher Mitarbeiter am Zoologischen Institut II der Universität Karlsruhe (ab 11/1992 gefördert durch DFG Kl 745/2-2) 1992-1995 Habilitandenstipendium der DFG (Kl 745/2) 12/1995 Habilitation im Fach Zoologie an der Fakultät für Bio- und Geowissenschaften der Universität Karlsruhe 1993-1996 Wissenschaftlicher Assistent (C1) am Zoologischen Institut II der Universität Karlsruhe 1996-1999 Hochschuldozent (C2) am Zoologischen Institut II der Universität Karlsruhe 1999-1999 Lehrstuhlvertretung (C4) am Zoologischen Institut II der Universität Karlsruhe 1999 Abteilungsleiter der Abteilung „Ökophysiologie und Aquakultur“ am Leibniz-Institut für Gewässerökologie und Binnenfischerei, Forschungsverbund Berlin e. V. 2002 C3-S-Professur für Endokrinologie an der Humboldt-Universität zu Berlin und Abteilungsleiter der Abteilung „Ökophysiologie und Aquakultur“ am Leibniz-Institut für Gewässerökologie und Binnenfischerei, Forschungsverbund Berlin e. V. seit 08/2010 W3-Professur für Endokrinologie an der Humboldt-Universität zu Berlin und Abteilungsleiter der Abteilung „Ökophysiologie und Aquakultur“ am Leibniz-Institut für Gewässerökologie und Binnenfischerei, Forschungsverbund Berlin e. V.

Forschungsthemen

Endokrinologie Physiologie Ökotoxikologie Aquakultur

Forschungsprojekte

TitelLaufzeitBeschreibung
Verlust der Nacht 2010 - 2013 Ursachen und Folgen künstlicher Beleuchtung für Umwelt, Natur und Mensch
ASTAF-PRO 2010 Aquaponik-System zur emissionsfreien Tomaten und Fisch-Produktion in Gewächshäusern bei größtmöglicher Wassereinsparung.
Verlust der Nacht: Teilprojekt: Impact of artificial light on fish physiology 2010-2013 Verlust der Nacht hinsichtlich der Fischphysiologie
Umweltverschmutzung durch endokrine Disruptoren im Nil 2010 -2012 Responses of environmental pollution in Nile tilapia of EDCs and theri biomarkers
INNOVATE 01.01.2012 - 31.12.2016 Nachhaltige Nutzung des Itaparica Stausees im semi-ariden Norden Brasiliens
Hier - Zur Datenbank der Bibliothek

    2015

  • Kumar, Vimal; Johnson, Andrew C.; Trubiroha, Achim; Tumova, Jitka; Ihara, Masaru; Grabic, Roman; Kloas, Werner; Tanaka, Hiroaki; Kroupova, Hana Kocour (2015):
    The challenge presented by progestins in ecotoxicological research: a critical review.
    Environmental Science and Technology, 49 (5): 2625-2638.
  • Tamschick, Stephanie; Rozenblut-Koscisty, Beata; Bonato, Lucio; Dufresnes, Christophe; Lymberakis, Petros; Kloas, Werner; Ogielska, Maria; Stöck, Matthias (2015):
    Sex chromosome conservation, DMRT1 phylogeny and gonad morphology in diploid palearctic green toads (Bufo viridis subgroup).
    Cytogenetic and Genome Research, 144 (4): 315-324.
  • Gröner, Frederike; Zikova, Andrea; Kloas, Werner (2015):
    Effects of the pharmaceuticals diclofenac and metoprolol on gene expression levels of enzymes of biotransformation, excretion pathways and estrogenicity in primary hepatocytes of Nile tilapia (Oreochromis niloticus).
    Comparative Biochemistry and Physiology C, 167: 51-58.
  • Cobo, Cristobal; Makhutu, Mary; Lumsdon, Alexander E.; Thompson, Kim D.; Jung, Rainer; Kloas, Werner; Knopf, Klaus (2015):
    The adjuvant effect of low frequency ultrasound when applied with an inactivated Aeromonas salmonicida vaccine to rainbow trout (Oncorhynchus mykiss).
    Vaccine, 33 (11): 1369-1374.
  • Brüning, Anika; Hölker, Franz; Franke, Steffen; Preuer, Torsten; Kloas, Werner (2015):
    Spotlight on fish: light pollution affects circadian rhythms of European perch but does not cause stress.
    Science of the Total Environment, 511: 516-522.
  • 2014

  • VanDerKraak, Glen; Hosmer, Alan J.; Hanson, Mark L.; Kloas, Werner; Solomon, Keith R. (2014):
    Effects of atrazine in fish, amphibians, and reptiles: an analysis based on quantitative weight of evidence.
    Critical Reviews in Toxicology, 44: 1-66.
  • Pietsch, Constanze; Schulz, Carsten; Rovira, Pere; Kloas, Werner; Burkhardt-Holm, Patricia (2014):
    Organ damage and hepatic lipid accumulation in carp (Cyprinus carpio L.) after feed-borne exposure to the mycotoxin, Deoxynivalenol (DON).
    Toxins, 6 (2): 756-778.
  • Kroupova, Hana Kocour; Trubiroha, Achim; Lorenz, Claudia; Contardo-Jara, Valeska; Lutz, Ilka; Grabic, R.; Kocour, Martin; Kloas, Werner (2014):
    The progestin levonorgestrel disrupts gonadotropin expression and sex steroid levels in pubertal roach (Rutilus rutilus).
    Aquatic Toxicology, 154: 154-162.
  • Pietsch, Constanze; Michel, Christian; Kersten, Susanne; Valenta, Hana; Dänicke, Sven; Schulz, Carsten; Kloas, Werner; Burkhardt-Holm, Patricia (2014):
    In vivo effects of deoxynivalenol (DON) on innate immune responses of carp (Cyprinus carpio L.).
    Food and Chemical Toxicology, 68: 44-52.
  • Urbatzka, Ralph; Lorenz, Claudia; Wiedemann, Caterina; Lutz, Ilka; Kloas, Werner (2014):
    Steroid exposure during larval development of Xenopus laevis affects RNA expression of the reproductive pituitary-gonodal axis in a sex- and stage-dependent manner.
    Comparative Biochemistry and Physiology C, 160: 1-8.
  • 2013

  • Hermelink,Björn;Wuertz, Sven;Rennert, Bernhard;Kloas, Werner;Schulz, Carsten; (2013):
    Temperature control of pikeperch (Sander lucioperca) maturation in recirculating aquaculture systems - induction of puberty and course of gametogenesis.
    Aquaculture, 400: 36-45.
  • Bazyar Lakeh,Amir Abbas;Kloas,Werner;Jung,Rainer;Ariav,Ra'anan;Knopf,Klaus; (2013):
    Low frequency ultrasound and UV-C for elimination of pathogens in recirculating aquaculture systems.
    Ultrasonics Sonochemistry, 20 (5): 1211-1216.
  • Zikova,Andrea;Lorenz,Claudia;Lutz,Ilka;Pflugmacher,Stephan;Kloas,Werner; (2013):
    Physiological responses of Xenopus laevis tadpoles exposed to cyanobacterial biomass containing microcystin-LR.
    Aquatic Toxicology, 128: 25-33.
  • Frank,Sabrina;Godehardt, Saskia;Nachev, Milen;Trubiroha,Achim;Kloas,Werner;Sures, Bernd; (2013):
    Influence of the cestode Ligula intestinalis and the acanthocephalan Polymorphus minutus on levels of heat shock proteins (HSP70) and metallothioneins in their fish and crustacean intermediate hosts.
    Environmental Pollution, 180: 173-179.
  • Franke,Steffen;Brüning,Anika;Hölker,Franz;Kloas,Werner; (2013):
    Study of biological action of light on fish.
    Journal of Light & Visual Environment, 37 (4): 194-204.
  • 2012

  • Kroupova, Hana;Trubiroha, Achim;Wuertz, Sven;Frank, Sabrina Nadine ;Sures, Bernd;Kloas, Werner; (2012):
    Nutritional status and gene expression along the somatotropic axis in roach (Rutilus rutilus) infected with the tapeworm Ligula intestinalis.
    General and Comparative Endocrinology, 177 (2): 270-277.
  • Wuertz, Sven;Hermelink, Björn;Kloas, Werner ;Schulz, Carsten; (2012):
    Pike perch in recirculation aquaculture.
    Global Aquaculture Advocate, 15 (4): 46-47.
  • Schaefer, Fabian;Kloas, Werner;Wuertz, Sven; (2012):
    Arapaima: Candidate for freshwater culture.
    Global Aquaculture Advocate, 15 (6): 50-51.
  • Zikova,Andrea;Lorenz,Claudia;Lutz,Ilka;Pflugmacher,Stephan;Kloas,Werner; (2012):
    Physiological responses of Xenopus laevis tadpoles exposed to cyanobacterial biomass containing microcystin-LR.
    Aquatic Toxicology, (128): 25-33.
  • Hermelink,Björn;Würtz,Sven;Rennert,Bernhard;Kloas,Werner;Schulz, Carsten; (2012):
    Temperature control of pikeperch (Sander lucioperca) maturation in recirculating aquaculture systems—induction of puberty and course of gametogenesis.
    Aquaculture, (400): 36-45.
  • Frank,Sabrina;Godehardt, Saskia;Nachev, Milen;Trubiroha,Achim;Kloas,Werner;Sures,Bernd; (2012):
    Influence of the cestode Ligula intestinalis and the acanthocephalan Polymorphus minutus on levels of heat shock proteins (HSP70) and metallothioneins in their fish and crustacean intermediate hosts.
    Environmental Pollution, (180): 173-179.
  • Bazyar Lakeh, Amir Abbas;Kloas,Werner;Jung, Rainer;Ariav, Ra\'anan;Aagaard,Per;Knopf,Klaus; (2012):
    Low frequency ultrasound and UV-C for elimination of pathogens in recirculating aquaculture systems.
    Ultrasonics Sonochemistry, (20): 1211-1216.
  • Hoffmann,Frauke;Kloas,Werner; (2012):
    Effects of environmentally relevant concentrations of the xeno-androgen, methyldihydrotestosterone, on male and female mating behavior in Xenopus laevis.
    Chemosphere, 87 (11): 1246-1253.
  • Hoffmann,Frauke;Kloas,Werner; (2012):
    Estrogens can disrupt amphibian mating behavior.
    PLoS One, 7 (2)
  • Hoffmann,Frauke;Kloas,Werner; (2012):
    The synthetic progestogen, Levonorgestrel, but not natural progesterone, affects male mate calling behavior of Xenopus laevis.
    General and Comparative Endocrinology, 176 (3): 385-390.
  • Osman,Alaa G.M.;Abuel-Fadl, Khaled Y. ;Kloas,Werner; (2012):
    In situ evaluation of the genotoxic potential of the river Nile: II. Detection of DNA strand-breakage and apoptosis in Oreochromis niloticus niloticus (Linnaeus, 1758) and Clarias gariepinus (Burchell, 1822).
    Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 747 (1): 14-21.
  • Trubiroha,Achim;Kroupova,Hana;Würtz,Sven;Kloas,Werner; (2012):
    Up-regulation of gonadotropin mRNA-expression at the onset of gametogenesis in the roach (Rutilus rutilus): evidence for an important role of brain-type aromatase (cyp19a1b) in the pituitary.
    General and Comparative Endocrinology, 178 (3): 529-538.
  • Hoffmann,Frauke;Kloas,Werner; (2012):
    The antiestrogens tamoxifen and fulvestrant abolish estrogenic impacts of 17a-ethinylestradiol on male calling behavior of Xenopus laevis.
    PLoS One, 7 (9)
  • 2011

  • Contardo-Jara,Valeska;Lorenz,Claudia;Pflugmacher,Stephan;Nützmann,Gunnar;Kloas,Werner;Wiegand,Claudia; (2011):
    Molecular effects and bioaccumulation of levonorgestrel in the non-target organism Dreissena polymorpha..
    Environmental Pollution, 159 (1): 38-44.
  • Bazyar Lakeh, Amir Abbas ; Farahmand, Hamid; Mirvaghefi, Alireza; Kloas, Werner; Peterson, Brian C.; Würtz, Sven (2011):
    GH and IGF-I induction by passive immunisation of rainbow trout Oncorhynchus mykiss (Walbaum) using a somatostatin-14 antibody..
    Aquaculture, 159 (1): 99-103.
  • Osman,Alaa G.M.;Abd El Reheem, Abd-El-Baset M.;Moustafa, Mohsen A.;Mahmoud, Usama M.;Abuel-Fadl, Khaled Y.;Kloas,Werner; (2011):
    In situ evaluation of the genotoxic potential of the river Nile: I. micronucleus and nuclear lesion tests of erythrocytes of Oreochromis niloticus niloticus (Linnaeus, 1758) and Clarias gariepinus (Burchell, 1822). .
    Toxicological & Environmental Chemistry, 93 (5): 1002-1017.
  • Trubiroha,Achim;Kroupova,Hana;Frank,Sabrina;Sures,Bernd;Kloas,Werner; (2011):
    Inhibition of gametogenesis by the cestode Ligula intestinalis in roach (Rutilus rutilus) is attenuated under laboratory conditions..
    Parasitology, 138 (5): 648-659.
  • Frank,Sabrina,Nadine;Faust,Steffen;Kalbe,Martin;Trubiroha,Achim;Kloas,Werner;Sures,Bernd; (2011):
    Fish hepatic glutathione-S-transferase activity is affected by the cestode parasites Schistocephalus solidus and Ligula intestinalis: evidence from field and laboratory studies..
    Parasitology, 138 (7): 939-944.
  • Hermelink,Björn; Würtz, Sven; Trubiroha, Achim; Rennert, Bernhard; Kloas, Werner; Schulz, Carsten; (2011):
    Influence of temperature on puberty and maturation of pikeperch, Sander lucioperca.
    General and Comparative Endocrinology, 172 (2): 282-292.
  • Kroupova, Hanna; Trubiroha, Achim; Würtz, Sven; Kloas, Werner (2011):
    Stage-dependent differences in RNA composition and content affect the outcome of expression profiling in roach (Rutilus rutilus) ovary.
    Comparative Biochemistry and Physiology A, 159 (2): 141-149.
  • Lorenz, Claudia; Contardo-Jara, Valeska; Pflugmacher, Stephan; Wiegand, Claudia; Nützmann, Gunnar; Lutz, Ilka; Kloas, Werner (2011):
    The synthetic gestagen levonorgestrel impairs metamorphosis in Xenopus laevis by disruption of the thyroid system.
    Toxicological Sciences, 123 (1): 94-102.
  • Pietsch,Constanze;Neumann,Nadja;Preuer,Torsten;Kloas,Werner; (2011):
    In vivo treatment with progestogens causes immunosuppression of carp Cyprinus carpio leucocytes by affecting nitric oxide production and arginase activity..
    Journal of Fish Biology, 79 (1): 53-69.
  • Meric, Ilknur;Würtz, Sven;Kloas, Werner;Wibbelt, Gertrud;Schulz, Carsten; (2011):
    Cottonseed oilcake as a protein source in feeds for juvenile tilapia (Oreochromis niloticus): Antinutritional effects and potential detoxification by iron supplementation.
    Israeli Journal of Aquaculture-Bamidgeh, 63 (588)
  • Lorenz,Claudia; Contardo-Jara, Valeska; Krüger, Angela; Viehmann, Viola; Wiegand, Claudia; Pflugmacher, Stephan; Nützmann, Gunnar; Lutz,Ilka ; Kloas,Werner (2011):
    The Synthetic Gestagen Levonorgestrel Disrupts Sexual Development in Xenopus laevis by Affecting Gene Expression of Pititary Gonadotroppins and Gonadal Steroidogenic Enzymes.
    Toxicological Sciences, 124 (2): 311-319.
  • Reiser,Stefan;Wuertz,Sven;Schroeder,Jan;Kloas,Werner;Hanel,Reinhold (2011):
    Risks of seawater ozonation in recirculation aquaculture - Effects of oxidative stress on animal welfare of juvenile turbot (Psetta maxima, L.).
    Aquatic Toxicology, 105 (3): 508-517.
  • Contardo Jara,Valeska;Lorenz,Claudia;Pflugmacher,Stephan;Nützmann,Gunnar;Kloas,Werner;Wiegand,Claudia; (2011):
    Exposure to human pharmaceuticals Carbamazepine, Ibuprofen and Bezafibrate causes molecular effects in Dreissena polymorpha.
    Aquatic Toxicology, 105 (3): 428-437.
  • 2010

  • Hoffmann F;Kloas W; (2010):
    An environmentally relevant endocrine-disrupting antiandrogen, vinclozolin, affects calling behavior of male Xenopus laevis.
    Hormones and Behavior, 58 (4): 653-659.
  • Hölker F;Moss T;Griefahn B;Kloas W;Voigt C;Henckel D;Hänel A;Kappeler P;Völker S;Schwope A;Franke S;Uhrlandt D;Fischer J;Klenke R;Wolter C;Tockner K; (2010):
    The dark side of light: a transdisciplinary research agenda for light pollution policy.
    Ecology and Society, 15 (4): 1-11.
  • Lutz I;Kloas W;Kikuyama S; (2010):
    Sixth International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology ISAREN 2009 Introduction.
    General and Comparative Endocrinology, 168 (2): 169-170.
  • Osman AGM;Kloas W; (2010):
    Water quality and heavy metal monitoring in water, sediments, and tissues of the African catfish Clarias gariepinus (Burchell, 1822) from the river Nile. Egypt.
    Journal of Environmental Protection, 1: 389-400.
  • Reiser S;Schroeder JP;Würtz S;Kloas W;Hanel R; (2010):
    Histological and physiological alterations in juvenile turbot (Psetta maxima, L.) exposed to sublethal concentrations of ozone-produced oxidants in ozonated seawater.
    Aquaculture, 307 (1): 157-164.
  • Osman,Alaa G.M.;Kloas,Werner; (2010):
    Water quality and heavy metal monitoring in water, sediments, and tissues of the African catfish Clarias gariepinus (Burchell, 1822) from the river Nile, Egypt. .
    Journal of Environmental Protection, 1 (4): 389-400.
  • Zikova A;Trubiroha A;Wiegand C;Würtz S;Rennert B;Pflugmacher S;Kopp R;Mares J;Kloas W; (2010):
    Impact of microcystin containing diets on physiological performance of Nile tilapia (Oreochromis niloticus) concerning stress and growth.
    Environmental Toxicology and Chemistry, 29 (3): 561-568.
  • Trubiroha A;Kroupova H;Würtz S;Frank S;Sures B;Kloas W; (2010):
    Naturally-induced endocrine disruption by the parasite Ligula intestinalis (Cestoda) in roach (Rutilus rutilus).
    General and Comparative Endocrinology, 166 (2): 234-240.
  • Wolf JC;Lutz I;Kloas W;Springer TA;Holden LR;Krueger HO;Hosmer AJ; (2010):
    Effects of 17ß-estradiol exposure on Xenopus laevis gonadal histopathology.
    Environmental Toxicology and Chemistry, 29 (5): 1091-1105.
  • Contardo Jara V;Kloas W;Pflugmacher S;Nützmann G;Wiegand C; (2010):
    The beta receptor blocker Metoprolol alters detoxification processes in the non-target organism Dreissena polymorpha.
    Environmental Pollution, 158 (6): 2059-2066.
  • Behrends T;Urbatzka R;Krackow S;Elepfandt A;Kloas W; (2010):
    Mate calling behavior of male South African clawed frogs (Xenopus laevis) is suppressed by the antiandrogenic endocrine disruptor flutamide.
    General and Comparative Endocrinology, 168 (2): 269-274.
  • Hermelink B;Urbatzka R;Wiegand C;Pflugmacher S;Lutz I;Kloas W; (2010):
    Aqueous leaf extracts display endocrine activities in vitro and disrupt sexual differentiation of male Xenopus laevis tadpoles in vivo.
    General and Comparative Endocrinology, 168 (2): 245-255.
  • Massari A;Urbatzka R;Cevasco A;Canesi L;Lanza C;Scarabelli L;Kloas W;Mandich A; (2010):
    Aromatase mRNA expression in the brain of adult Xenopus laevis exposed to Lambro river water and endocrine disrupting compounds.
    General and Comparative Endocrinology, 168 (2): 262-268.
  • Opitz R;Kloas W; (2010):
    Developmental regulation of genes involved in thyroid gland activity and growth during Xenopus laevis metamorphosis.
    General and Comparative Endocrinology, 168 (2): 199-208.
  • Urbatzka R;Lorenz C;Lutz I;Kloas W; (2010):
    Expression profiles of LH beta, FSH beta and their gonadal receptor mRNAs during sexual differentiation of Xenopus laevis tadpoles.
    General and Comparative Endocrinology, 168 (2): 239-244.
  • Zikova A;Trubiroha A;Wiegand C;Würtz S;Rennert B;Pflugmacher S;Kopp R;Mares J;Spurny P;Kloas W; (2010):
    Impact of microcystin containing diets on physiological performance of Nile tilapia (Oreochromis niloticus) concerning detoxification.
    Journal of Environmental Monitoring, 12 (12): 2276-2281.
  • 2009

  • Kloas W;Lutz I;Springer T;Krueger H;Wolf J;Holden L;Hosmer AJ; (2009):
    Does atrazine influence larval development and sexual differentiation in Xenopus laevis.
    Toxicological Sciences, 107 (2): 376-384.
  • Kloas W;Urbatzka R;Opitz R;Würtz S;Behrends T;Hermelink B;Hoffmann F;Jagnytsch O;Kroupova H;Lorenz C;Neumann N;Pietsch C;Trubiroha A;Ballegooy Cv;Wiedemann C;Lutz I; (2009):
    Endocrine disruption in aquatic vertebrates.
    Annals of the New York Academy of Sciences, 1163: 187-200.
  • Kloas W;Lutz I;Urbatzka R;Springer T;Krueger H;Wolf J;Holden L;Hosmer AJ; (2009):
    Does atrazine affect larval development and sexual differentiation of South African clawed frogs?.
    Annals of the New York Academy of Sciences, 1163: 437-440.
  • Oehlmann J;Schulte-Oehlmann U;Kloas W;Jagnytsch O;Lutz I;Kusk KO;Wollenberger L;Santos EM;Paull GC;Van Look KJW;Tyler C; (2009):
    A critical analysis of the biological impacts of plasticizers on wildlife.
    Philosophical Transactions of the Royal Society of London : Ser. B, Biological Sciences, 364: 2047-2062.
  • Opitz R;Schmidt F;Braunbeck T;Würtz S;Kloas W; (2009):
    Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.
    Molecular and Cellular Endocrinology, 298: 101-114.
  • Orton F;Lutz I;Kloas W;Routledge E; (2009):
    Endocrine disrupting effects of herbicides and pentachlorophenol: In vitro and in vivo evidence.
    Environmental Science and Technology, 43: 2144-2150.
  • Pietsch C;Neumann N;Knopf K;Würtz S;Kloas W; (2009):
    Progestogens cause immunosuppression of stimulated carp (Cyprinus carpio L.) leukocytes in vitro.
    Comparative Biochemistry and Physiology C, 150: 16-24.
  • Trubiroha A;Frank S;Würtz S;Sures B;Kloas W; (2009):
    Endocrine disrupting effects in fish induced by parasites.
    Integrated Environmental Assessment and Management, 5: 354-355.
  • Trubiroha A;Würtz S;Frank S;Sures B;Kloas W; (2009):
    Expression of gonadotropin subunits in roach (Cyprinidae, Rutilus rutilus) infected with plerocercoids of the tapeworm Ligula intestinalis (Cestoda: Pseudophyllidea).
    International Journal for Parasitology, 39: 1465-1473.
  • Urbatzka R;Watermann B;Lutz I;Kloas W; (2009):
    Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-alpha reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms.
    Journal of Molecular Endocrinology, 43: 209-219.
  • Geßner J;Kamerichs CM;Kloas W;Würtz S; (2009):
    Behavioural and physiological responses in early life phases of Atlantic sturgeon (A. oxyrinchus) towards different substrate.
    Journal of Applied Ichthyology, 25: 83-90.
  • Lorenz C;Opitz R;Lutz I;Kloas W; (2009):
    Teratogenic effects of chronic treatment with corticosterone on tadpoles of Xenopus laevis.
    Annals of the New York Academy of Sciences, 1163: 454-456.
  • Lorenz C;Opitz R;Lutz I;Kloas W; (2009):
    Corticosteroids disrupt amphibian metamorphosis by complex modes of action including increased prolactin expression.
    Comparative Biochemistry and Physiology C, 150 (2): 314-321.
  • 2008

  • Binner M;Kloas W;Hardewig I; (2008):
    Energy allocation in juvenile roach and burbot under different temperature and feeding regimes.
    Fish Physiology and Biochemistry, 34 (2): 103-116.
  • Cevasco A;Urbatzka R;Bottero S;Massari A;Pedemonte F;Kloas W;Mandich A; (2008):
    Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology.
    Comparative Biochemistry and Physiology C, 147: 241-251.
  • Lutz I;Kloas W;Springer TA;Holden LR;Wolf JC;Krueger HO;Hosmer AJ; (2008):
    Development, standardization and refinement of procedures for evaluating effects of endocrine active compounds on development and sexual differentation of Xenopus laevis.
    Analytical and Bioanalytical Chemistry, 390: 2031-2048.
  • Oehlmann J;Schulte-Oehlmann U;Oetken M;Bachmann J;Lutz I;Kloas W; (2008):
    Superfeminization as an effect of bisphenol A in Marisa cornuarietis.
    Ecotoxicology and Environmental Safety, 69: 577-579.
  • Ogunji J;Toor R;Schulz C;Kloas W; (2008):
    Growth performance, nutrient utilization of Nile tilapia Oreochromis niloticus fed housefly maggot meal (magmeal) diets.
    Turkish Journal of Fisheries and Aquatic Sciences, 8: 141-147.
  • Ogunji J;Kloas W;Wirth M;Neumann N;Pietsch C; (2008):
    Effect of housefly maggot meal (magmeal) diets on the performance, concentration of plasma glucose, cortisol and blood characteristics of Oreochromis niloticus fingerlings.
    Journal of Animal Physiology and Animal Nutrition, 92: 511-518.
  • Osman AGM;Mekkawy IA;Verreth J;Würtz S;Kloas W;Kirschbaum F; (2008):
    Monitoring of DNA breakage in embryonic stages of the African catfish Clarias gariepinus (Burchell, 1822) after exposure to lead nitrate using alkaline comet assay.
    Environmental Toxicology, 23 (6): 679-687.
  • Pietsch C;Vogt R;Neumann N;Kloas W; (2008):
    Production of nitric oxide by carp (Cyprinus carpio L.) kidney leukocytes is regulated by cyclic 3`,5`-adenosine monophosphate.
    Comparative Biochemistry and Physiology A, 150: 58-65.
  • Viganò L;Benfenati E;Van Cauwenberge A;Eidem JK;Erratico C;Goksøyr A;Kloas W;Maggioni S;Mandich A;Urbatzka R; (2008):
    Estrogenicity profile and estrogenic compounds determined in river sediments by chemical analysis, ELISA and yeast assays.
    Chemosphere, 73: 1078-1089.
  • Ogunji J;Kloas W;Wirth M;Schulz C;Rennert B; (2008):
    Housefly maggot meal (magmeal) as a protein source for Oreochromis niloticus (Linn.).
    Asian Fisheries Science, 21 (3): 319-331.
  • Osman,Alaa G.M.;Mekkawy,I.A.;Verreth, J.;Würtz,Sven;Kloas,Werner; (2008):
    Monitoring of DNA breakage in embryonic stages of the African catfish Clarias gariepinus (Burchell, 1822) after exposure to lead nitrate using alkaline comet assay. .
    Environmental Toxicology, 23: 679-687.
  • 2007

  • Würtz S;Nitsche A;Jastroch M;Geßner J;Klingenspor M;Kirschbaum F;Kloas W; (2007):
    The role of the IGF-I system for vitellogenesis in maturing female sterlet, Acipenser ruthenus Linnaeus, 1758.
    General and Comparative Endocrinology, 150 (1): 140-150.
  • Würtz S;Geßner J;Kirschbaum F;Kloas W; (2007):
    Expression of IGF-I and IGF-I receptor in male and female sterlet, Acipenser ruthenus - Evidence for an important role in gonad maturation.
    Comparative Biochemistry and Physiology A, 147 (1): 223-230.
  • Köhler H;Kloas W;Schirling M;Lutz I;Reye A;Langen J;Triebskorn R;Nagel R;Schönfelder G; (2007):
    Sex steroid receptor evolution and signalling in aquatic invertebrates.
    Ecotoxicology, 16 (1): 131-143.
  • Urbatzka R;Bottero S;Mandich A;Lutz I;Kloas W; (2007):
    Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression.
    Comparative Biochemistry and Physiology C, 144: 310-318.
  • Urbatzka R;Lutz I;Kloas W; (2007):
    Ontogeny of aromatase, steroid-5-alpha-reductase type 1 and type 2 mRNA expression in gonads and in brain of Xenopus laevis.
    General and Comparative Endocrinology, 153: 280-288.
  • Urbatzka R;Van Cauwenberge A;Maggioni S;Viganò L;Mandich A;Benfenati E;Lutz I;Kloas W; (2007):
    Androgenic and antiandrogenic activities in water and sediment samples from the river Lambro, Italy.
    Chemosphere, 67: 1080-1088.
  • 2006

  • Würtz S;Nitsche A;Geßner J;Kirschbaum F;Kloas W; (2006):
    IGF-I and its role in maturing gonads of female sterlet, Acipenser ruthenus Linnaeus, 1758.
    Journal of Applied Ichthyology, 22: 346-353.
  • Würtz S;Lutz I;Geßner J;Löschau P;Hogans B;Kirschbaum F;Kloas W; (2006):
    The influence of rearing density as environmental stressor on cortisol response of Shortnose sturgeon (Acipenser brevirostrum).
    Journal of Applied Ichthyology, 22: 269-274.
  • Sures B;Lutz I;Kloas W; (2006):
    Effects of infection with Aguillicola crassus and simultaneous exposure with Cd and 3,3`,4,4`,5-pentachlorobiphenyl (PCB 126) on the levels of cortisol and glucose in European eel (Anguilla anguilla)..
    Parasitology, 132: 281-288.
  • Oehlmann J;Schulte-Oehlmann U;Bachmann J;Oetken M;Lutz I;Kloas W;Ternes T; (2006):
    Bisphenol A induces superfeminization in the ramshorn snail Marisa cornuarietis (Gastropoda: Prosobranchia) at environmentally relevant concentrations..
    Environmental Health Perspectives, 114: 127-133.
  • Opitz R;Hartmann S;Blank T;Braunbeck T;Lutz I;Kloas W; (2006):
    Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles..
    Toxicological Sciences, 90: 337-348.
  • Opitz R;Lutz I;Nguyen N;Scanlan T;Kloas W; (2006):
    Analysis of thyroid hormone receptor betaA mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action..
    Toxicology and Applied Pharmacology, 212: 1-13.
  • Schulte-Oehlmann U;Albanis T;Allera A;Bachmann J;Berntsson P;Beresford N;Carnevali D;Ciceri F;Dagnac T;Falandysz J;Galassi S;Hala D;Janer G;Jeannot R;Jobling S;King I;Klingmüller D;Kloas W;Kusk O;Levada R;Lo S;Lutz I;Oehlmann J;Oredsson S;Porte C;Rand-Weaver M;Sakkas V;Sugni M;Tyler C;Van Aerle R;Ballegooy Cv;Wollenberger L; (2006):
    COMPRENDO: Focus and approach..
    Environmental Health Perspectives, 114: 98-100.
  • Urbatzka R;Lutz I;Opitz R;Kloas W; (2006):
    Luteinizing hormone, follicle stimulating hormone, and gonadotropin releasing hormone mRNA expression of Xenopus laevis in response to endocrine disrupting compounds affecting reproductive biology..
    General and Comparative Endocrinology, 146: 119-125.
  • Jagnytsch O;Opitz R;Lutz I;Kloas W; (2006):
    Effects of tetrabromobisphenol A on larval development and thyroid hormone-regulated biomarkers of the amphibian Xenopus laevis.
    Environmental Research, 101 (3): 340-348.
  • Opitz R;Trubiroha A;Lorenz C;Lutz I;Hartmann S;Blank T;Braunbeck T;Kloas W; (2006):
    Expression of sodium-iodide symporter mRNA in the thyroid gland of Xenopus laevis tadpoles: developmental expression, effects of antithyroidal compounds, and regulation by TSH..
    Journal of Endocrinology, 190: 157-170.
  • Kloas W;Lutz I; (2006):
    Amphibians as model to study endocrine disrupters.
    Journal of Chromatography A, 1130: 16-27.
  • 2005

  • Klann A;Levy G;Lutz I;Müller C;Kloas W;Hildebrandt J; (2005):
    Estrogen-like effects of UV screen 3-(4-methylbenzylidene)-camphor (4-MBC, Eusolex 6300) on cell proliferation and gene induction in mammalian and amphibian cells.
    Environmental Research, 97: 274-281.
  • Mandich A;Benfenati E;Cronin M;Goksøyr A;Grosvik B;Kloas W;Van Cauwenberge A;Viganò L; (2005):
    Environmental agent susceptibility assessment using existing and novel biomarkers as rapid noninvasive testing methods.
    Annals of the New York Academy of Sciences, 1040: 381-386.
  • Opitz R;Braunbeck T;Bögi C;Pickford D;Nentwig G;Oehlmann J;Tooi O;Lutz I;Kloas W; (2005):
    Description and initial evaluation of a Xenopus metamorphosis assay for detection of thyroid system-disrupting activities of environmental compounds.
    Environmental Toxicology and Chemistry, 24: 653-664.
  • Jastroch M;Würtz S;Kloas W;Klingenspor M; (2005):
    Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis.
    Physiological Genomics, 22: 150-156.
  • Lutz I;Zhang J;Opitz R;Kloas W;Xu Y;Menzel R;Steinberg CEW; (2005):
    Environmental signals: synthetic humic substances act as xeno-estrogen and affect the thyroid system of Xenopus laevis.
    Chemosphere, 61: 1183-1188.
  • Lutz I;Blödt S;Kloas W; (2005):
    Regulation of estrogen receptors in primary cultured hepatocytes of the amphibian Xenopus laevis as estrogenic biomarker and its application in environmental monitoring.
    Comparative Biochemistry and Physiology C, 141: 384-392.
  • 2004

  • Ekanem AP;Obiekezie A;Kloas W;Knopf K; (2004):
    Effects of crude extracts of Mucuna pruriens (Fabaceae) and Carica papaya (Caricaceae) against the protozoan fish parasite Ichthyophthirius multifiliis.
    Parasitology Research, 92: 361-366.
  • Levy G;Lutz I;Krüger A;Kloas W; (2004):
    Bisphenol A induces feminization in Xenopus laevis tadpoles.
    Environmental Research, 94: 102-111.
  • Takei Y;Joss J;Kloas W;Rankin C; (2004):
    Identification of angiotensin I in several vertebrate species: its structural and functional evolution.
    General and Comparative Endocrinology, 135: 286-292.
  • Levy G;Lutz I;Krüger A;Von Tümpling W;Kloas W; (2004):
    Retinol binding protein as a biomarker to assess endocrine disrupting compounds in the environment.
    Analytical and Bioanalytical Chemistry, 378: 676-683.
  • Steinberg CEW;Höss S;Kloas W;Lutz I;Meinelt T;Pflugmacher S;Wiegand C; (2004):
    Hormonelike effects of humic substances on fish, amphibians, and invertebrates.
    Environmental Toxicology, 19: 409-411.
  • Ekanem AP;Meinelt T;Kloas W;Knopf K; (2004):
    Early life stage toxicity of extracts from the African fish poison plants Tephrosia vogelii Hook. f. and Asystasia vogeliana Benth. on zebrafish embryos..
    Journal of Fish Biology, 65: 489-494.
  • 2003

  • Bögi C;Schwaiger J;Ferling H;Mallow U;Steineck C;Kalbfus W;Negele RD;Lutz I;Kloas W; (2003):
    Endocrine effects of environmental pollution on Xenopus laevis and Rana temporariax.
    Environmental Research, 93: 195-201.
  • Schmid AC;Lutz I;Kloas W;Reinecke M; (2003):
    Thyroid hormone stimulates hepatic IGF-1 mRNA expression in a bony fish, the tilapia Oreochromis mossambicus, in vitro and in vivo.
    General and Comparative Endocrinology, 130: 129-134.
  • 2002

  • Kloas W; (2002):
    Amphibians as model for the study of endocrine disruptors.
    International Review of Cytology, 216: 1-57.
  • Meinelt T;Kloas W; (2002):
    Was sind endokrin wirksame Substanzen und wie beeinträchtigen sie unsere Fische?.
    Fischerei & Fischmarkt in Mecklenburg-Vorpommern, 2: 40-42.
  • Mosconi G;Carnevali O;Franzoni M;Cottone E;Kloas W;Lutz I;Yamamoto K;Kikuyama S;Polzonetti-Magna A; (2002):
    Environmental estrogens and reproductive biology in amphibians.
    General and Comparative Endocrinology, 126: 125-129.
  • Bögi C;Levy G;Lutz I;Kloas W; (2002):
    Functional genomics and sexual differentiation in amphibians.
    Comparative Biochemistry and Physiology B, 133: 559-570.
  • Sures B;Scheef G;Klar B;Kloas W;Taraschewski H; (2002):
    Interaction between cadmium exposure and infection with the intestinal parasite Moniliformis moniliformis (Acanthocephala) on the stress hormone levels in rats.
    Environmental Pollution, 119: 333-340.